“The Devil Wears Prada 2” opens globally this week, 20 years after the original became a huge sleeper hit for 20th Century Fox. For the 64th Golden Globes on Jan. 15, 2007, at the Beverly Hilton ballroom, Meryl Streep was 57, at the zenith of her career to that point.

The film earned three Golden Globe nominations, including Streep as best actress in a musical or comedy for her performance as imperious fashion magazine editor Miranda Priestly in “The Devil Wears Prada.” On a $41 million budget, the comedy had earned $326.7 million worldwide over the previous summer, making it the highest grossing film of Streep’s career — and the highest earning movie of the 10 films nominated for best drama and best musical/comedy at that year’s Globes. On a telecast that included Leonardo DiCaprio, Will Smith, Jack Nicholson, Eddie Murphy and Brad Pitt, Streep was arguably the biggest start of the night.

So it was to no one’s surprise when presenter Joaquin Phoenix announced Streep as the winner in her category. As the ballroom rose to a standing ovation, she took to the stage to Madonna’s “Vogue” — a nod to one of the inspirations for Priestly, Vogue editor Anna Wintour. (Disney has used that song extensively to promote “The Devil Wears Prada 2.”)

It was Streep’s sixth Golden Globe win (she’s since earned two more, as well as the Cecil B. DeMille Award in 2017), and her turn at the mic led to a generous, funny and profound speech.

“I’m really thrilled — I think I’ve worked with everybody in the room,” she said, putting on her glasses. “Yes, I have!”

She first congratulated “the nominees in all the categories for best actress” by their first names: “This has been such a fun year to watch movies because of you gals.” She thanked director David Frankel and screenwriter Aline Brosh McKenna, and then her costars, “delicious Emily Blunt, darling Annie Hathaway, dreadful Stanley Tucci, for the difficult, difficult job they had making me seem monstrous.” (Blunt, nominated for supporting actress for “Prada,” had won earlier that night for supporting actress in a series, miniseries or TV film for the BBC America movie “Gideon’s Daughter.”)

Streep also shouted out 20th Century Fox studio chief “Tommy Rothman, who signs the checks,” and then paused: “And Rupert” — as in News Corporation mogul Rupert Murdoch — “who signs his checks.”

Finally, Streep noted that the runaway success of “Prada” at the box office was “because it was playing on every theater screen across America.” Whereas most audiences had been unable to see many other films nominated that night — Streep named several, including “Little Children,” “Pan’s Labyrinth” and “The Queen.”

If that bothers anyone watching, she said, “you have to go down to your theater manager and ask him why.” With a knowing glance over her glasses,  and evoking her character’s two word catchphrase, Streep concluded: “It’s amazing how much you can get if you quietly, clearly and authoritatively demand it. That’s all.”

Twenty years later, “The Devil Wears Prada 2” is poised to become an even bigger hit. Time will tell whether Streep will also return to the Globes stage.